Which 1986 hit song featured a collaboration between hip-hop pioneers run-d. m. c. and the hard rock group aerosmith as well as an influential music video which played a pivotal role in mainstreaming rap music?

The correct answer is Walk This Way.

The song was originally created in 1975 and performed by Aerosmith, but a decade later, a hip-hop group called Run-D. M. C. covered the song (Stephen Tyler also appeared in it) and the song became an instant hit.