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30 March, 03:43

If nondisjunction occurs during anaphase I of meiosis I, this means that at least one pair of homologous chromosomes did not separate. The end result is two cells that have an extra copy of one chromosome and two cells that are missing that chromosome.

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  1. 30 March, 04:39
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    Meiotic nondisjunction

    In humans, n + 1 designates a cell with 23 chromosomes plus an extra copy of one for a total of 24 chromosomes. n - 1 designates a cell missing a chromosome for a total of only 22 chromosomes in humans.

    If nondisjunction occurs during anaphase II of meiosis II, it means that at least one pair of sister chromatids did not separate. In this scenario, two cells will have the normal haploid number of chromosomes. Additionally, one cell will have an extra chromosome (n + 1) and one will be missing a chromosome (n - 1).
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