For the hydrolysis of atp to adp + i, the free energy change is - 7.3 kcal/mol under standard conditions (1 m concentration of both reactants and products). in the cellular environment, however, the free energy change is about - 13 kcal/mol. what can we conclude about the free energy change for the formation of atp from adp and i under cellular conditions?

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Biology

Riley Bird

28 August, 18:30

For the hydrolysis of atp to adp + i, the free energy change is - 7.3 kcal/mol under standard conditions (1 m concentration of both reactants and products). in the cellular environment, however, the free energy change is about - 13 kcal/mol. what can we conclude about the free energy change for the formation of atp from adp and i under cellular conditions?

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Darius Boone · Answer 1

We can conclude that there is a much higher [ATP] than [ADP + Pi] normally in cells, which favors the hydrolysis pathway.

In other words, reactants (ATP) >> products (ADP + Pi), which creates a more negative G.

ΔG = G (products) - G (reactants)