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23 July, 05:40

Using your knowledge of activators and repressors, hypothesize two ways in which transcription of the lct gene could be turned off.

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  1. 23 July, 08:54
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    One hypothesis would be that there are allosteric repressors that bind to RNA-polymerase and change its conformation. This way, it's unable to bind to the promoter for lct gene.

    Another hypothesis would be that the repressors bind to a silencer or operator sequence of the lct gene. This prevents transcription of the gene even though the RNA polymerase may be capable of binding to the promoter.
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