Which condition is a rare, transmissible, progressive fatal disease of the central nervous system characterized by spongiform degeneration of the gray matter of the brain?

The correct answer is " Creutzfeldt-Jakob disease".

Creutzfeldt-Jakob disease is a disease which causes severe dementia and myoclonus. a couple of sclerosis is a persistent, degenerative, modern ailment of the CNS characterized with the aid of the prevalence of small patches of demyelination within the brain and spinal wire. Parkinson's disease is related to reduced tiers of dopamine because of destruction of pigmented neuronal cells inside the substantia nigra within the basal ganglia of the brain. Huntington sickness is a chronic, modern, hereditary disorder of the nervous machine that outcomes in modern involuntary dancelike movements and dementia.