Makers of generic drugs are required to show that their generic drugs do not differ significantly from the "reference" or brand name drugs that they imitate. one aspect in which the generic drugs might differ is their extent of absorption in the blood. twelve subjects were available for the study. six were randomly selected to receive the generic drug first and then, after a washout period, receive the "reference" drug. the remaining six received the "reference" drug first, followed by the generic drug after the washout period.

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Biology

Marissa

19 October, 07:41

Makers of generic drugs are required to show that their generic drugs do not differ significantly from the "reference" or brand name drugs that they imitate. one aspect in which the generic drugs might differ is their extent of absorption in the blood. twelve subjects were available for the study. six were randomly selected to receive the generic drug first and then, after a washout period, receive the "reference" drug. the remaining six received the "reference" drug first, followed by the generic drug after the washout period.

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Casey · Answer 1

What type of experiment is this? - Matched Pairs Design

A matched-pairs design is a type of randomized block design that has two treatment conditions (in this case, the generic drug and the reference drug), and pairs subjects based on common variables (in this case, six subjects were randomly selected to receive the generic drug first and then, after a washout period, receive the "reference" drug, while the remaining six were given the "reference" drug first, and then the generic drug after the washout period)