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12 November, 13:24

Which is considered the most widely used group of antibiotics due to their bactericidal nature, their resistance to beta-lactamases, and their activity against a broad spectrum of pathogens?

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  1. 12 November, 15:39
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    The beta-lactam group of antibiotics such as penicillins (i. e. Amoxicillin), cephalosporins (i. e. Cefuroxime), and carbapenems (i. e. Meropenem) is the most widely used group of antibiotics. Beta-lactams are bactericidal. Beta-lactams have no innate resistance to beta-lactamases (enzymes produced by bacteria to break down beta-lactam antibiotics), but they can be paired with a beta-lacamase inhibitor such as Clavulanic acid. Later generations of beta-lactams may offer resistance to beta-lactamases. Beta-lactams offer activity against a broad spectrum of bacterial pathogens, including gram-positive, gram-negative, and (in higher doses, such as Cefazolin) anaerobic coverage.
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