If a mouse inherits a deletion in the shh enhancer, what effect would you expect to see?

Question

Biology

Valerie Farmer

13 August, 04:10

If a mouse inherits a deletion in the shh enhancer, what effect would you expect to see?

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Answers (2)

Know the Answer?

Janessa Cross · Answer 1

Janessa Cross 13 August, 05:20

0

Abnormal limb development

Smith · Answer 2

You would expect to see abnormal limb development.

A long-range shh enhancer regulates expression in the developing limb and fin is associated with preaxial polydactyly. Consequences of deletion and mutation of the limb enhancer in a mouse would be an abnormal development of the limb which is regulated by the Shh enhancer.