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24 October, 16:17

Label the sketch below to explain how a ras mutation leads to cancer

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  1. 24 October, 19:44
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    The answers of this question are the following:

    (1) a growth factor that binds to

    (2) its receptor in the plasma membrane.

    The signal is relayed to (3) a G protein called Ras. Like all G proteins, Ras is active when GTP is bound to it.

    Ras passes the signal to (4) a series of protein kinases.

    The last kinase activities (5) a transcription activator that turns on one or more genes for proteins that stimulate the cell cycle. If a mutation makes Ras or any other pathway component abnormally active, excessive cell division and cancer may result.
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