Which neurotransmitter does lsd principally operate on? dopamine serotonin acetylcholine norepinephrine?

LSD or Lysergic acid diethylamide, the drug of choice of folks during the 60’s, mainly has psychedelic effects. It distorts or alters awareness of surroundings, perceptions, or even feelings. It also induces hallucinations. LSD works by binding to serotonin receptors. Serotonin receptors both have excitatory and inhibitory neurotransmission effects. That explains why LSD is neither stimulating or sedating. The explanation for the psychedelic effects of LSD is still not completely understood.