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16 April, 01:10

Methotrexate interferes with the metabolism of

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  1. 16 April, 05:06
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    Methotrexate interferes with the metabolism of Folate. Methotrexate is an antineoplastic anti-metabolite and enters cells via the reduced folate carrier, which also transports the naturally occurring reduced folates, including the most common form found in food, 5-methyltetrahydrofolate. MTX causes the body to get rid of more folate as waste than usual which causes a folate deficiency.
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