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22 February, 00:11

What can a deficiency of growth hormone during bone formation cause? what can a deficiency of growth hormone during bone formation cause? decreased osteoclast activity inadequate calcification of bone increased osteoclast activity decreased epiphyseal plate activity?

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  1. 22 February, 01:21
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    The deficiency of growth hormone during bone formation would cause a decreased proliferation of the epiphyseal plate cartilage. Growth hormone is a peptide hormone secreted by the pituitary gland under the control of the hypothalamus. It directly through IGF-I stimulates osteoblasts proliferation and activity, promoting bone formation. In addition it also stimulates osteoclast differentiation and activity, promoting bone resorption. Therefore, growth hormone is an important hormone in bone formation.
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