Why is MgATP2-, instead of ATP4-, a substrate for the hexokinase reaction? Select two correct phrases. Mg2 + prevents ATP hydrolysis. Hexokinase cannot bind ATP when it is not complexed with Mg2+. Mg2 + makes the? (terminal) phosphorus atom of ATP more accessible to electrophilic attack by a glucose - OH group. Mg2 + shields the negative charges of two of the phosphate oxygen atoms of ATP. Mg2 + makes the? (terminal) phosphorus atom of ATP more accessible to nucleophilic attack by a glucose - OH group.

Question

Biology

Haylee Li

5 May, 04:28

Why is MgATP2-, instead of ATP4-, a substrate for the hexokinase reaction? Select two correct phrases. Mg2 + prevents ATP hydrolysis. Hexokinase cannot bind ATP when it is not complexed with Mg2+. Mg2 + makes the? (terminal) phosphorus atom of ATP more accessible to electrophilic attack by a glucose - OH group. Mg2 + shields the negative charges of two of the phosphate oxygen atoms of ATP. Mg2 + makes the? (terminal) phosphorus atom of ATP more accessible to nucleophilic attack by a glucose - OH group.

+5

Answers (1)

Know the Answer?

Brooklynn Blanchard · Answer 1

Mg is able to give off two of its electrons to other molecule, not four. ATP, in this case is the aceptor of those electrons

Two correct answers are:

1) Hexokinase cannot bind active ATP when it is not complexed with Mg2+

2) Mg2 + makes the terminal phosphorus atom of ATP more accessible to nucleophilic attack by a glucose-OH group

Explanation:

As Mg occurs naturally as ion Mg++, it is able to give off only two of its electrons to other molecule, then it is possible for ATP to receive two electrons of Mg, forming MgATP2-

The hexokinase reaction, here cited, corresponds to the glucose phosphorylation of its sixth carbon to produce glucose-6-P, which is a glycolysis intermediate. In this way glucose is activated (ATP is initially invested to energize glucose). Later on, Glyceraldehide-3-P is produced, and finally converted to pyruvate, NADH2 and ATP