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20 November, 01:59

Cytochalasins bind actin and block actin microfilament assembly. Cells treated with cytochalasins will not divide. How do cytochalasins block cell division?

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  1. 20 November, 03:04
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    The correct answer will be-cytochalasin act by blocking the polymerization of actin filaments.

    Explanation:

    Cytochalasins are the metabolite product obtained from the fungus which has can bind the actin filament and block the polymerization of actin.

    Cytochalasins bind the barbed end of the microtubule which represents the plus of the microtubule, it then blocks the assembly and disassembly of the actin filaments and thus blocks the cell division.

    The cytochalasins are used by the researchers to study the process which takes place during the cell division.

    Thus, cytochalasin act by blocking the polymerization of actin filaments.

    Cytochalasins are fungal metabolites that have the ability to bind to actin filaments and block polymerization and the elongation of actin

    As a result of the inhibition of actin polymerization, cytochalasins can change cellular morphology, inhibit cellular processes such as cell division, and even cause cells to undergo apoptosis.

    Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which then blocks both the assembly and disassembly of individual actin monomers from the bound end

    The use of cytochalasins has allowed researchers to better understand actin polymerization, cell motility, ruffling, cell division, contraction, and cell stiffness.
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