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5 December, 07:41

The outcome of a single crossover between nonsister chromatids in the inversion loop of an inversion heterozygote varies depending on whether the inversion is of a pericentric or paracentric type. What differences are expected?

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  1. 5 December, 08:50
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    Pericentric inversions produce four chromatids with one centromere each, while paracentric inversions produce an acentric and dicentric chromoatid (both inviable).

    Explanation:

    Pericentric and paracentric inversions are part of the chromosomal alteration that occurs during a process called inversion, where the alterations that occur when a portion of the chromosome separates but are joined to the inverted chromosome again. The genetic material remains the same, however, the disposition of information occurs in a exchanged manner.

    During inversion, the result of a single cross between non-sister chromatids in the inversion loop of an inversion heterozygote would vary depending on whether the inversion is of the pericentric or paracentric type.

    In this case, the Pericentric Inversion would happen when the region undergoing inversion involved the centromere, in which case four chromotids with one centromere each would be produced. On the other hand, the paracentric inversion would happen when the inverted region did not involve the centromere, the result of which would be the production of a sharp and dicentric chromoid (both unviable).
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