Suppose there is a gene called VID that codes for the incredible ability to play any video game. This gene is 360 nucleotides long, with no introns. The wildtype version codes for a protein consisting of 120 amino acids. Some people cannot play video games well at all. Their VID gene was isolated and sequenced and found to have a nonsense mutation. The resulting non-functional VID protein consisted of just 20 amino acids. However, some rare individuals who also carry this same nonsense mutation in their gene do have a functional VID protein consisting of the full 120 wildtype amino acids. Which of the following most likely accounts for these rare individuals with a mutation in their gene but a fully functional protein.

Question

Biology

Denzel Cannon

4 April, 00:44

Suppose there is a gene called VID that codes for the incredible ability to play any video game. This gene is 360 nucleotides long, with no introns. The wildtype version codes for a protein consisting of 120 amino acids. Some people cannot play video games well at all. Their VID gene was isolated and sequenced and found to have a nonsense mutation. The resulting non-functional VID protein consisted of just 20 amino acids. However, some rare individuals who also carry this same nonsense mutation in their gene do have a functional VID protein consisting of the full 120 wildtype amino acids. Which of the following most likely accounts for these rare individuals with a mutation in their gene but a fully functional protein.

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Answers (2)

Know the Answer?

Chasity Austin · Answer 1

Chasity Austin 4 April, 00:53

0

the 120 wildtype amino acids

Susan Roberson · Answer 2

We can say that the VID gene that encoded the ability for a person to play a video game, have a chain length of 360 nucleotides. Said wild type has 120 amino acids. Three codons always code for an amino acid, if we divide the number of nucleotides by the number of amino acids we realize that both the mutated gene and the wild gene have the same number of nucleotides.

Explanation:

The exercise mentions that the VID gene has a nonsense mutation in 20 of the amino acids. The nonsense mutation occurs during the completion stage of translation. A conclusion to this phenomenon could be that the tRNA would have a mutation, for which an amino acid is replaced, thus forming the functional protein.