What is the relationship between the bud and the parent

Over one third of the subjects were negative both for family history and any disorder of their own and 20% reported a problem in both themselves and in one or both parents. These findings lend only partial support for Winokur's depression spectrum disease hypothesis, in that diagnosed children of depressed-only families have a 30% chance of exhibiting substance abuse or dependence alone, whereas diagnosed children of alcoholic-only families have only a 7% chance of exhibiting depression alone.