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21 October, 16:53

Steroid hormones bind to receptors inside the cell and alter their conformation. The hormone-receptor complex is then transported into the nucleus, where it can directly affect gene expression. To get from the location where the receptor binds the hormone to its site of action, the receptor-hormone complex must (circle one):

a) become water soluble by binding to a carrier molecule.

b) enter the smooth endoplasmic reticulum.

c) be transported through the nuclear pore complex.

d) undergo another conformational change.

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  1. 21 October, 18:51
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    c) be transported through the nuclear pore complex.

    Explanation:

    To alter gene expression, the hormone-receptor complex must be transported into the location where gene itself stored. Since gene stored inside nucleus, the hormone-receptor complex have to reach it by getting inside nuclear pore complex. The complex will bind to specific region of the gene and will promote or inhibit the transcription of that gene.
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