Which of the following distinguishes prophase 1 of meiosis from prophase of mitosis?

A. homologous chromosomes pair up

B. spindle forms

C. nuclear membrane breaks down

D. chromosomes become visible

The correct answer is A). Homologous chromosomes pair up.

Explanation:

During prophase 1, it occurs chromosomes condensation. The principal difference with the mitosis prophase is that during meiosis prophase 1, each chromosome gets carefully in pair with its homologous chromosome. They do so to make the crossing-over possible, stage where they interchange their parts.