Which one of the following statements is true regarding transcription-coupled repair? Transcription-coupled repair involves all the major nucleotide excision repair proteins, as well as RNA polymerase. Transcription-coupled repair occurs in response to the stalling of a ribosome. Transcription-coupled repair corrects damage in mRNA. Transcription-coupled repair occurs only during S phase of the cell cycle.

The correct answer is "Transcription-coupled repair involves all the major nucleotide excision repair proteins, as well as RNA polymerase".

Explanation:

Transcription-coupled DNA repair (TCR) is a type of DNA repair that prioritizes transcribed strands of actively transcribed genes. TCR is a complex pathway that involves all the major nucleotide excision repair proteins, as well as RNA polymerase. RNA polymerase stalled at DNA lesions and recruits a series of nucleotide excision repair proteins to assess the damage.