Which is an example of a substitution mutation?

O CAG - TTA-CAC mutates to CAG - GAC - TTA - CAC

CAG - TTA - CAC mutates to CAG - TTA - CAC-AT

CAT - GGC - TAC mutates to CAT - GGC - TAG

CAT - GGC - TAC mutates to ATG - GCT - AC

The answer is C

CAT - GGC - TAC mutates to CAT - GGC - TAG is the right answer

Explanation:

because substitution mutation is the change in the single base which result in change in codon which encode different amino acid and protein sequence changes.

for example in this

CAT - GGC - TAC encodes HGY protein

now after change in single nucleotide from C to G

CAT - GGC - TAG which encodes HG stop codon