Glycogenolysis and glycogen synthesis are regulated in such a way that neither process is active at the same time. During the fasted state, (ratio of insulin to glucagon is low) which of the following best characterizes the regulation of these pathways:
A. Both glycogen phosphorylase and glycogen synthase are phosphorylated
B. Both glycogen phosphorylase and glycogen synthase are dephosphorylated
C. Glycogen phosphorylase is phosphorylated and glycogen synthase is dephosphorylated
D. Glycogen phosphorylase is dephosphorylated and glycogen synthase is phosphorylated
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