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14 May, 09:19

The drug vinblastine disrupts microtubule polymerization. How would adding vinblastine to a cell affect the constitutive secretory pathway?

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  1. 14 May, 09:57
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    Transport vesicles will not be brought to either the Golgi apparatus or the plasma membrane.

    Explanation:

    Microtubules forms part of the structure of the cytoskeleton. It is a polymer of tubulins.

    Apart from maintaining the cell structure, cytoskeleton plays a role in transportation in a cell.

    A Constructive secretory pathway is an exocytosis process found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream

    A disruption on microtubules will lead to a change in structure of the cytoplasm. It will not be able to perform its function therefore transport vesicles will not be brought to either the plasma membrane or the golgi apparatus.
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