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9 October, 21:50

Destruction of the paraventricular nucleus (PVN) with electrolytic lesions has been shown to produce hyperphagia (overeating) in rats. Injections of local anesthetic into the PVN may also stimulate eating. Likewise, injections of NE into the PVN also produce feeding in rats. What does this information suggest about the effect of NE on the firing rate of neurons in the PVN? A general principle relating changes in the rate of neural firing to changes in the rate of a specific behavior (such as feeding) can be derived from this information. What is this principle?

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  1. 10 October, 00:39
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    The answer is that NE injection has inhibitory effects on the paraventricular nucleus VPN.

    Explanation:

    It can be said that the destruction of the paraventricular nucleus (PVN) would produce a hyperphagia, on the other hand, the injection of norepinephrine (NE) would increase the feeding in the rats. This is because NE injection has inhibitory effects on the paraventricular nucleus. If neuronal activation in the paraventricular nucleus is increased, food intake by rats would be decreased.
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