Fungi are differentiated from the other major groups of eukaryal microbes by

There cell wall is made of chitin

Explanation

Eukaryotic microorganism are those organisms that have cells containing membrane bound organelles such as the nucleus and the mitochondria. Prokaryotes have no bound organelles.

Fungi is an example of a eukaryote. However, its cells are different from the rest of the groups because it is made of chitin. A fibrous polysaccharide that support the cell structure.