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13 October, 10:49

Why doesn't a negative stain colorize the cells in the smear?

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  1. 13 October, 12:57
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    It is impossible for a negative stain to colorize the cells in the smear because the chromogen of the negative stain carries a negative charge and is repelled as a result of the negative charge present on the surface of the cell. In this light, the stain can only colorize the background, thus permitting visibility of the capsule and the cell.
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