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13 September, 20:28

List a few terms that are unique for regulation of transcription in eukaryotic cells?

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  1. 13 September, 23:15
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    Eukaryotic transcription refers to an elaborate procedure, which is used by the eukaryotic cells to duplicate the genetic information present in DNA into the units of RNA replica. The transcription of the gene takes place in both prokaryotic and eukaryotic cells. The expression of eukaryotic genes is mainly monitored at the level of the beginning of transcription, though in certain cases, transcription may be monitored and attenuated at subsequent steps.

    Like in bacteria, the transcription in eukaryotic cells is monitored by the proteins, which combines with the unique regulatory sequences and modulate the activity of RNA polymerase. The intricate task of monitoring the expression of gene in various kinds of cells of multicellular species is achieved mainly by the combined activities of various different transcriptional regulatory proteins.

    In supplementation, the packaging of DNA into chromatin and its variation by methylation produce further levels of complexity to the control of eukaryotic gene expression. The transcription in bacteria is monitored by the combination of proteins to the cis-acting sequences, which regulate the transcription of adjacent genes.

    The same kind of cis-acting sequence monitors the expression of eukaryotic genes. These sequences have been determined in mammalian cells mainly by the application of gene transfer assays to examine the activity of suspected regulatory regions of cloned genes.
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