The 5′ end of the DNA growing strand during DNA replicationA) is the part of the strand that is added last. B) does not contain a phosphate group on the ribose. C) is the part of the strand that is added first. D) is the end of both strands of DNA in a double helix. E) could contain the base uracil.

Question

Biology

Maximillian Santos

23 January, 19:32

The 5′ end of the DNA growing strand during DNA replicationA) is the part of the strand that is added last. B) does not contain a phosphate group on the ribose. C) is the part of the strand that is added first. D) is the end of both strands of DNA in a double helix. E) could contain the base uracil.

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Yareli · Answer 1

C) is the part of the strand that is added first

Explanation:

DNA replication occur by a semiconservative model. During DNA replication the strands of DNA are unbounded by DNA helicase and stabilized by single cell binding proteins.

The primase enzyme build the short primers and DNA polymerase synthesize the new strand of DNA. One restriction for DNA polymerase is that it can only synthesize the DNA strand in 5' to 3' direction. That's why 5' end of DNA is always synthesized first.

The leading strand is synthesized continuously and lagging strand is synthesized in fragments known as okazaki fragments because of DNA polymerase ability to synthesize the strand in only 5' to 3' direction. These fragments are joined by DNA ligase and RNA primers are also replaced by DNA polymerase.