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30 July, 22:41

Imagine a scenario where Barr bodies are not due to random inactivation, but rather, the silencing is due to paternal imprinting (paternal allele is silenced). How would this change the frequency of red/green colorblindness between men and women in the population?

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  1. 31 July, 00:17
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    If Barr bodies are not due to random inactivation, but rather, the silencing is due to paternal imprinting then the frequency of men and women differs.

    Explanation:

    Red-green color blindness: color blindness is an X-linked recessive disorder. The male having this disease will transmit his X chromosome (with the mutation) to his daughter, who will then be a carrier of the disease.

    If Barr bodies are not due to random inactivation, but rather, the silencing is due to paternal imprinting then the frequency of men and women differs.

    Male inherit its X chromosome only from mother and no X chromosome from father, having one Y chromosome but female receive one X chromosome from father and one from mother, having no Y chromosome, So if the paternal allele is silenced then the males are no affected.
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