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Yesterday, 14:26

Which of the following represents the treatment option most likely to avoid the evolution of drug-resistant HIV (assuming no drug interactions or side effects) ?

A) using a series of NAs, one at a time, and changed about once a week

B) using a single PI, but slowly increasing the dosage over the course of a week

C) using high doses of NA and a PI at the same time for a period not to exceed one day

D) using moderate doses of NA and two different PIs at the same time for several months

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  1. Yesterday, 15:25
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    D

    Explanation:

    This is called HAART (Highly Active Anti-Retroviral Therapy) and it is currently the mainstay treatment of HIV.

    Most of HAART consist in the use of 2 NRTI or NNRTI and the addition of one PI or a Integrase Inhibitor. However, the use of one NRTI plus 2 PI is valid.
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