Which of the following is NOT true of phospholipid bilayers?

A. The interior of phospholipid bilayers is a highly hydrophobic environment.

B. Membrane budding requires transient breakages in the bilayer membrane.

C. Phospholipid bilayers separate the cell from the exterior environment as well as from compartments within the cell.

D. The chemical properties of phospholipids lead to the spontaneous formation of bilayers.

The correct answer is option B. membrane budding requires transient breakages in the bilayer membrane.

Explanation:

Phospholipid bilayer consists of two layers of the phospholipids with a hydrophilic head externally and hydrophobic tail internally in each phospholipid molecule. It is the surrounding membrane that encloses the cell cytoplasm and contents.

Internally phospholipid bilayer are hydrophobic due to hydrophobic in nature. It acts as a barrier that separates the cell from the external environment. It is possible to spontaneous formation of bilayers is due to to the chemical properties.

Thus, the correct answer is option B.