What of the following is a major difference between site-specific recombination and transposition?

A. Transposition is much more carefully controlled than site-specific recombination.

B. Site-specific recombination involves two defined sequence elements, whereas transposition involves the movement of a specific sequence to a nonspecific site in the DNA.

C. Transposition involves two defined sequence elements, whereas site-specific transposition involves the movement of a specific sequence to a nonspecific site in the DNA.

D. Site-specific recombination is much more carefully controlled than transposition.

The correct answer is option B. "Site-specific recombination involves two defined sequence elements, whereas transposition involves the movement of a specific sequence to a nonspecific site in the DNA".

Explanation:

Site-specific recombination is a type of genetic recombination that involves two defined sequence elements. The recombination is catalyzed by Site-specific recombinases (SSRs) that recognizes and binds to the short DNA sequences that are recognized. On the other hand, transposition is a type of genetic recombination that involves the movement of a specific sequence to a nonspecific site in the DNA. Transposition is mediated by transposases, a large super-family of enzymes from both prokaryotes and eukaryotes.