Microbial cells are grouped into two major groups based on the separation of their genetic material from the cytoplasm. Which are these two groups?

Eukaryotic microbes and prokaryotic microbes

Explanation:

Some microbes such as bacteria do not have a membrane-bound nucleus. So, their genetic material lies in the cytoplasm itself. These microbes are called prokaryotic microbes. All the bacterial species are prokaryotes. Example: E. coli.

On the other hand, some microbes have a well define nucleus to house their genetic material. These microbes are called eukaryotic microbes. Fungi and protists are the eukaryotic microbes. Example: plasmodium and slime mold.