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7 September, 09:15

A mature focal adhesion may have a surface area of 2 um?. This focal adhesion can resist a force of approximately 5 nN/um before breakage. Each integrin-ligand interaction in a focal adhesion can resist a force of approximately 50 pN before being disrupted. Approximately how many integrin molecules are present in the 2 um2 focal adhesion?

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  1. 7 September, 12:20
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    Surface area of a mature focal adhesion is equal to 2 um. Therefore,

    Force resisted by focal adhesion is equal to 5 nN/um.

    Ans=500 integrim
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