Identification and location of genes on chromosomes that might affect cholesterol metabolism has been difficult because many of the genes that affect this trait interact, a phenomenon that is called epistasis. T or F?

True, the identification and location of genes and their effect has been difficult because of the phenomenon of epistasis.

Explanation:

Epistasis happens when the effect of a gene (locus) depends on one or more genes being present, that is. When epistatic mutations occur, they have different effects when they are in combination with when they are not. It occurs due to interactions between or within genes, which leads to unpredictable effects.