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28 June, 19:30

How would the deletion of the shine-dalgarno sequence affect a bacterial mrna?

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  1. 28 June, 22:43
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    Answer: Translation initiation cannot take place, preventing translation (protein synthesis)

    Explanation:

    The Shine-Dalgarno Sequence is a sequence found in the messenger RNA of bacteria. It s a ribosomal binding site located around 8 bases upstream of the start codon AUG, which indicates where translation must start.

    To carry out protein synthesis, the ribosome (the organelle where translation takes place) reads the sequence of mRNA bases that encode for that protein.

    The Shine-Dalgarno Sequence recruits the ribosome to the messenger RNA that is going to be translated, then it alignes this molecule with the start codon to initiate protein synthesis.

    If this sequence is absent, then the translation can not take place because the messenger RNA is not able to bind to the ribosome.
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