What kind of information would be required if karyotype analysis were to be used to detect the genetic disorders of real organisms?

In the field of biology, karyotype can be described as the complete array of chromosomes that an individual possesses.

To use karyotype for determining the genetic disorders, a person must have knowledge about the normal karyotype so that the defected karyotype can be detected by comparison from the normal karyotype. The deletions, insertions can easily be recognized by such a manner.