Uncle Mel suffers from depression and is having trouble sleeping. Some medications can increase the amount of neurotransmitter in the synapse by preventing its re-uptake into the presynaptic neuron or its degradation. This increases the level of the neurotransmitter in the synapse and prolongs its effects. Select which neurotransmitters you think might be a good target for anti-depressant drugs.

serotonin, norepinephrine, dopamine, acetylcholine, glutamate and GABA.

Explanation:

Antidepressants are drugs or drugs that act on the nervous system, whose function is to normalize the flow of neurotransmitters, which are molecules responsible for the nerve impulse from one neuron to another. Neurotransmitters leave one neuron, cross the synapse (space between two neurons), and activate the receptors on the next neuron. The most important neurotransmitters for this type of drug are serotonin, norepinephrine, dopamine, acetylcholine, glutamate and GABA.

There are selective serotonin or serotonin reuptake inhibitors. There are dual antidepressants that inhibit both serotonin and norepinephrine reuptake, known as the dual mechanism of action. There are certain antidepressants that also act on other neurotransmitters or have completely different mechanisms of action such as agomelatine that acts as a melatonin receptor agonist. Side effects vary according to the class to which the antidepressant belongs and also according to each person's tolerance.