The four main types of macromolecules are organic. what does organic mean in this context?

They have carbon in their structure.

Explanation:

All the four main types of macromolecules are organic in nature which means that they all have carbon in their structure. For example, carbohydrates are CHO compounds, proteins are monomers of amino acids which have at least one central carbon atom. Nucleic acids and lipids also have carbon atoms in their chemical structure.

The term "organic" refers to carbon and carbon bonding, which may be prevalent in macromolecules; it refers to various cell processes, like cellular respiration