How is a genetic disorder caused by a mutation different from a disorder caused by a chromosomal disorder?

Answer: A genetic disorder is cause by mutations or abnormalities within the genome, whereas chromosomal disorders have to do with the number of chromosomes a person has.

Explanation:

A person may be born with too many chromosomes, resulting in a chromosomal disorder. Some may be born with less chromosomes than necessary. Others are born with abnormal copies of chromosomes they already have--such as chromosome 21, which results in Down syndrome.