Which of the following is a nucleoside analog commonly used as a reverse transcriptase inhibitor in the treatment of HIV?

acyclovir

ribavirin

adenine-arabinoside

azidothymidine

Azidothymidine

Explanation:

Azidothymidine (AZT) is one of the nucleoside analogs that is used in the treatment of AIDS as it inhibits the process of reverse transcription of HIV (Human immunodeficiency virus).

The HIV replicates by making DNA copies of RNA through the process of reverse transcription. The process is driven by enzyme reverse transcriptase. Azidothymidine (AZT) serves to inhibit the activity of reverse transcriptase enzyme and thereby does not allow HIV to reproduce.