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25 November, 00:12

Which of the following is a change in the sequence that leads to formation of a stop codon?

missense mutation

nonsense mutation

silent mutation

deletion mutation

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Answers (1)
  1. 25 November, 04:02
    0
    -nonsense mutation

    Explanation:

    Non-sense mutations can be described as mutations that to formation of a non-sense or stop codon in mRNA made from mutated gene. There are a total of 64 codons, out of which 61 code for specific amino acids and 3 codons act as stop codon or non-sense codons.

    As these codons provide signal for termination of transcription, non-sense mutations lead to formation of a incomplete or truncated proteins due to premature termination of translation.

    Thus, the correct answer is 'second option.'
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