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21 October, 17:08

Albinism is inherited as autosomal recessive trait. The frequency of the disease in the population equals to 1:20 000. Calculate frequency of heterozygotes in population.

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  1. 21 October, 17:45
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    0.0139 - frequency of heterozygotes in the population

    Explanation:

    Let q to the power of 2 represents the frequency of the homozygous recessive (aa) = 1/20000 = 0.00005

    This, q = √q^2 = √0.00005 = 0.007

    Since p + q = 1

    p = 1 - 0.007 = 0.993

    Using the formula: p^2 + 2pq + q^2

    Where 2pq represents the frequency of the heterozygotes, thing we have

    2 x 0.007 x 0.993

    = 0.0139
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