How would selection against heterozygous individuals over many generations affect the frequencies of homozygous individuals? would the results of such selection depend on the initial frequencies of p and q? could you test this experimentally?

The selection against the heterozygous individuals would influence the frequencies of the homozygous individuals for many generations. If the selection of heterozygous individuals is not done, the frequency of the heterozygous individuals may decline in against the homozygous individuals.

Yes, the outcomes rely upon the initial frequencies of p and q of Hardy-Weinberg allele frequencies. An inference can be formulated in order to test the experimentation. For example, use Hardy-Weinberg equation for allele frequencies in a population, that is,

p2 + 2pq + q2 = 1, where p and q are the homozygous individuals, and 2pq is heterozygous. In the mentioned equation, the heterozygous individuals, that is, 2pq decreases and homozygous individuals, that is, p2 and q2 increases.

Answer to question 1:

The heterozygous individuals have two different types of alleles and homozygous contains the same types of alleles in the genome. The selection of heterozygous individuals over many generations lowers the frequencies of homozygous individuals.

'The selection means that the expected genotype will be produced by planned breeding of homozygous individuals of different types of genomes. Then the offspring will be heterozygous. the breeding of heterozygous can also have the 12 probability of heterozygous offspring.

Hence the frequency of homozygous will decrease.

Answer to question 2:

Yes, the results of selection depend upon the frequencies of p and q.

Explanation:

We can explain this by giving an example in which the frequency of pis more than the frequency of q in a population.

Then the homozygous p frequency will be more than the frequency of q.

The selection results are heterozygous genotype. As the p is more and q is less, so the frequency of heterozygous will also be low due to the low frequency of q.

Hence the q here act as the limiting factor for the results of selection.

Answer to question 3.

We can not test this experimentally.

Explanation:

Genetics test is not performed experimentally rather they are performed mathematically in form of Punnett square.

Genetics experiments involve reproduction. And the duration of human and other species reproduction is very long.

S the results are only predicted by the mathematical derivations and laws like Punnett square which is used to predict the genotype of offspring by parents genome.