Thermogenin, or uncoupling protein 1 (UCP1), found in brown adipose tissue plays an important role in thermoregulation. Use the First Law of Thermodynamics as well as key metabolic reactions to explain thermogenin's mechanism of action and regulation in cells. Use information from a recent research publication to support your answer.

The first law of thermodynamics explains that the energy of a system is converted, constantly modifying the internal energy of the system, this explains the function of thermogenin that generates increased thermal effects on body temperature (thermogenesis) without affecting the tremor mechanism.

Explanation:

One of the recent studies that explains this physiological mechanism is "Brown and Beige Adipose Tissues in Health and Disease." From the Pubmed page, thermogenin acts in relation to fat cells in brown tissue since these are the source of caloric energy (calories) that transform their energy to promote body thermoregulation.