What are two diseases that are caused by defective cell parts?

Two diseases caused my defective cells is HIV (human immunodeficiency virus) and AIDS (acquired immunodeficiency syndrome).

Parkinson's disease, Mitochondrial malfunctioning has been implicated in the pathogenesis of several neurodegenerative diseases, including Parkinson's disease (PD). The cause of dopaminergic cell death in PD is thought to involve oxidative stress and mitochondrial complex I dysfunction [17]. and Cell cycle and cell death