Determine the correct steps in the activation of pka, and then place them in the correct order, starting after the adenylyl cyclase reaction.

After the adenylyl cyclase reaction (which convert ATP into cyclic adenosine monophosphate-cAMP), cAMP level is directly increased. Next steps of PKA activation include:

• cAMP binding to regulatory subunits of PKA, as a result conformational change in the regulatory subunits of PKA is induced,

• catalytic subunits are detached and unleashed by regulatory subunits and as a result activated.