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22 January, 08:20

Identify the false statements regarding ketone bodies.

A. Ketone body synthesis is triggered when energy requirements are not met through carbohydrate catabolism.

B. Ketone bodies are formed directly from acetyl‑CoA.

C. Ketone body synthesis increases with increasing concentration of acetyl‑CoA.

D. Functional groups common to all ketone bodies are a carboxylate ion and a ketone.

E. Ketone bodies are formed in the liver.

F. Ketone bodies are able to form hydrogen bonds with water.

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  1. 22 January, 11:39
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    Option D is false

    Option E is false since it is incomplete

    Option C is false

    Explanation:

    Well, regarding option D it is considered false because the functional groups would be:

    Acetone (which is not used as an energy source, is exhaled or excreted as waste), Betahydroxybutyrate and acetoacetate (if not oxidized to be used as an energy source).

    In statement C it is false, because the formation of ketone bodies increases with the presence of acetylcoA, but acetone is one of those that will always be witnessed in a lower percentage, since it is excreted by the body as waste, both either by the airways in the exhalation (characteristic ketone breath) and in the urine (cetouria)

    And as for the E option, I consider it false because the ketone groups are formed in the liver and kidney.

    Greater proportion in hepatic mitochondria and to a lesser extent in the kidney
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