Which of the following address (es) the problems posed by chromatin during transcription?

a) In some instances, protein factors can interfere with chromatin structure at specific locations, opening sensitive sites.

b) The action of chromatin remodeling factors is involved, which require ATP hydrolysis to allow the promoter regions to accept the complex.

c) In some cases, the chromatin structure rearranges at the time of replication.

d) All of the listed statements are true.

Option D All of the listed statements are true

Explanation:

the major problem posed by chromatin during transcription includes its state at that moment in time. The chromatin might exist in a state that prevent the transcription machinery from accessing the DNA to carry out transcription and bring about gene expression. thus, its state can either allow for gene expression or not.

Thus, some factors/processes have been put in place to regulate this. This includes chromatin remodeling complexes that utilize the energy supplied by ATP hydrolysis to affect nucleosomes causing structure alterations, covalent histone modification that allows for unwinding of the DNA from nucleosome to allow for transcription to take lace.