Which treatment came the closest to restoring the ovariectomized rat to normal bone density? Which treatment came the closest to restoring the ovariectomized rat to normal bone density? Calcitonin saline estrogen fsh?

The answer would be estrogen

Ovariectomy is a procedure to remove ovaries. Ovary function is to produce estrogen. When the ovary is removed, the synthesis of estrogen stopped. Estrogen has a role in regulating osteocyte, osteoblast and osteoclast cell which regulate the bone formation. The absence of estrogen will increase the bone remodeling thus reducing bone density.